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Mol Cell Biochem 240:8398

Room-temperature storage accelerates aggregation

Louis, MO, United States), and trypsin from Roche Diagnostics (Mannheim, Germany)

doi: 10.1126/sciadv.abo5633 226 LiWWuWSongHWangFLiHChenLet al

At this point, the cell has reached the so-called Hayflick limit

In other words, the preclinical signal appears against a backdrop of controlled energy intake and activity, not as a standalone effect that overrides diet