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Small molecule SARM1 inhibitors recapitulate the SARM1-/- phenotype and allow recovery of a metastable pool of axons fated to degenerate

Y., Cheng, S

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Histopathologic and microscopic score Findings Histopathological analysis and lesion scoring were performed to elucidate the influence of the treatment on the cellular structures of the testicular tissue

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Further, on evaluating hepatic antioxidant capacity, it was significantly attenuated in MTX group in comparison with CTRL as demonstrated by the significantly lower hepatic GSH and SOD activity (Figures 3B, C)