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Under OS, HIF-1 is stabilized via nitrogen oxide (NOX)/ROS, which upregulates glycolytic enzymes (SLC2A1 and HK) and inhibits mitochondrial respiration via PDK1 activation [222]

In vivo infection experiments demonstrated that Klra17 -/- mice showed augmented splenomegaly and increased titers of S

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In health cells, cytosolic NADH is shuttled into mitochondria, where it is turned into NAD + by OXPHOS whereas in cancer cells, the conversion of NAD + to NADH in mitochondria is not sufficient for the high rate of glycolysis due to reduced OXPHOS

Antioxidant Properties NAC is acknowledged for its antioxidant properties and its contribution to redox equilibrium, which is often disrupted in various neurodegenerative diseases [4,17]

aureus with inhibitory diameters ranging from 13 to 15 mm and MIC values of 0.3120.625 mg/mL (Yiit et al., 2009)