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These effects are transient

This leads to a very distinct different type of treatment protocol for those who have a combined form

Proc Am Assoc Cancer Res 43:646, 2002

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GBA crosstalk occurs via multiple channels, with rapid neuronal signaling primarily by the vagus nerve, as well as the gut connectome (via the semi-autonomous ENS), with more delayed feedback being achieved through neuroendocrine and neuroimmune signals into the circulation [351, 506] in the form of gut-derived neurotransmitters (dopamine (DA), serotonin (5-HT), GABA, and histamine), hormones, and inflammatory mediators (i.e., cytokines)

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