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[132] [142] [143] Once nucleus accumbens FosB is sufficiently overexpressed, it begins to increase the severity of addictive behavior (i.e., compulsive drug-seeking) with further increases in its expression

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The size of these nanoformulations ranges from 25 nm to 2.5 mm, suggesting that they can carry almost all kinds of cargos to the target site with controlled distribution and flexibility [100]

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