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Beyond T and stromal compartments, innate immune cells can also rely on one-carbon-supported SAM to mount proinflammatory responses

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However, the increase in intracellular iron leads to increased levels of ROS and lipid metabolites [46], which enhances the sensitivity of tumor cells to ferroptosis and may be a breakthrough point for the treatment of some iron-rich or ROS-rich tumors (such as HCC, PDAC, BC, and NSCLC) [47]

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For one thing, a large number of RBCs will be eaten and digested with the help of Nramp1 in macrophages [27]

1.2 Glutathione v L-Glutathione 1.2.1 Glutathione dng kh Glutathione reduced - GSH (l Glutathione trng thi kh) hay cn c bit n l L-glutathione, l mt cht chng oxy ha, hin din nng micromolar (M) trong dch c th v nng millimolar (mM) trong m