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A clinical trial published in the Journal of Aging Science examining 40 women aged 40-65 demonstrated that topical GHK-Cu applied twice daily for 8 weeks "reduced wrinkle volume by 55.8% and wrinkle depth by 32.8%." The peptide appears to stimulate collagen and elastin production, enhance wound healing, and provide antioxidant effects

Interestingly, T-cell responses to the 22 conserved epitopes within this vaccine were enriched in individuals with asymptomatic infections relative to individuals with symptomatic infection [151]

10.1016/j.scr.2013.05.003 Stem Cell Res

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In both in vitro and in vivo models of PD, melatonin has been shown to decrease the expression of pro-inflammatory cytokines such as IL-1 and TNF- while elevating levels of anti-inflammatory factors

3 Age is also an important risk factor for T2D