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Signs and symptoms, if they do occur, might include fatigue, weakness, pale or yellowish skin, irregular heartbeats, shortness of breath, dizziness or lightheadedness, chest pain, cold hands and feet, and headaches

The intertwined dysregulation of copper and iron metabolism further exacerbates the disease by promoting apoptosis in lipid-rich foam cells and VSMCs, which are particularly vulnerable to metal-dependent cell death [195, 196]

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The peptide acts on multiple physiological pathways

doi: 10.1002/mnfr.200900246, 151

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