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In healthy individuals, CBF is tightly coupled to the metabolic demands of neurons (Claassen et al., 2021), however, it is unclear whether reduced CBF in ADRD is a cause or consequence of cerebral hypometabolism

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Cellular, molecular consequences of peroxisome proliferator-activated receptor- activation in ovarian cancer cells

PLC is a form of supplemental carnitine that has been shown to stimulate NO production, boost muscle carnitine, and facilitate the transport of free fatty acids into the mitochondria, where they can be used as fuel.[59] Human studies suggest that PLC may improve various aspects of exercise capacity in individuals with peripheral arterial disease or chronic heart failure,[60],[61] pointing toward its cardiovascular benefits

In this regard, several lines of evidence suggest that the metabolic engineering of PBPs could enhance crop resistance against plant pathogens (369, 370)

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