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Therefroe, the ammonia produced in the reverse reaction of GDH is excreted as NH 4 + in the urine, by first going through the urea cycle

10.1016/j.rmed.2016.06.015 Respir

This has been discussed in the next section so that readers can perceive the underlying concepts behind the development of pathways that contribute to drug resistance in cancer cells [11,12,13,14]

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Gasdermin D (GSDMD) is a prime candidate to integrate these pathological signals

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