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However, LepR GHR KO mice showed reduced body adiposity and serum leptin levels compared to control animals, whereas brain GHR KO mice had higher lean body mass and upregulation of hypothalamic GH-releasing hormone expression (GHRH

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These challenges include degradation by cellular nucleases, high renal clearance, and low penetration in biological membranes due to their negative charge

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Because TB-500 is often injected, some redness at the site can occur