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With this study, we aim to provide new therapeutic insights for optimizing postoperative gastrointestinal function recovery, particularly in utilizing simple and low-cost treatments such as vitamin B1 and B12, thereby promoting their clinical application

"Raise the skin into a 'tent' and insert the needle parallel to the body to release the dose under the skin, taking care to avoid self-injection

The 4 stages of B12 deficiency include (31): Stage 1: decreased levels of vitamin B12 in your blood Stage 2: low levels of vitamin B12 in your cells along with metabolic abnormalities Stage 3: neurological and psychological symptoms like anxiety, confusion, problems with balance, and others Stage 4: macrocytic anemia very large red blood cells (32) B12 deficiency can cause a variety of symptoms, including fatigue, headaches, depression, pale or yellow skin, mental impairment, and pain and inflammation in the mouth and tongue

As semaglutide can cause nutritional deficiencies such as vitamin B12 deficiency, many clinicians believe that maintaining optimal B12 levels can reduce fatigue, improve tolerance, and promote overall health during semaglutide therapy

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Studies have shown that HLA-DR2 haplotypes, particularly DRB5*01 + -DRB1*1501 + -DQB1*0602-, may play a role in the development of MS [152, 153]