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These gaps highlight the need for future research to move beyond descriptive associations toward systematic dissection of ferroptosis initiation mechanisms, cell type-specific contributions, and clinical validation

This approach should be medically supervised, with monitoring based on the patients health history and treatment goals

doi: 10.3389/fphar.2023.1256029 Received 10 July 2023 Accepted 11 August 2023 Published 29 August 2023 Volume 14 - 2023 Edited by Slvio Terra Stefanello, Westflischen Wilhelms-Universitt Mnster, Germany Reviewed by Phiwayinkosi V

Evidence from lymphoblasts from glaucoma patients points to mitochondrial alterations leading to impaired ATP production through defective function of Complex I of the electron transport chain (24, 25)