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These include enzymatic inactivation of drugs, drug target alteration and reduced transport of antibiotics to the bacterial cells

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Xue L., Wang L., Ou Z., et al., Clinical Efficacy of Fecal Microbiota Transplantation in Treatment of Parkinsons Disease With Constipation, Chin J Neurol 52, no

In the purine pathway, in addition to uric acid, studies have also identified inosine, an endogenous purine, as capable of downregulating the TNF-, IL-1, IL-6, and Macrophage inflammatory protein-2 (MIP-2) expression induced by LPS, and reducing MIP-1 (Figure 4)

This study provided valuable insight into how NAC bidirectionally crosses biological membranes and in particular the intact BBB

So, they make their conclusions on causation tenuous