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154 revealed that HOXA9 promoter methylation in circulating tumor DNA could serve as a biomarker in patients with platinum-resistant BRCA-mutated EOC undergoing treatment with PARP inhibitors

Step 3: Divide your doses

K.GreensteinD.SchapiroM.et al (2008)

Eagan, S

doi: 10.1007/s00592-022-01970-4 81 MarquesTMPattersonEWallROsullivanOFitzgeraldGFCotterPDet al

As -KG enters the TCA cycle, it gets oxidized to generate succinate and fumarate, which are cancer metabolites that produce ATP, NADH, and FADH2 [34] (Fig