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The Coordinating Center will monitor enrollment numbers monthly, and a contingency plan will be activated if recruitment falls behind schedule

IBD includes a spectrum of disorders such as Crohn's disease and ulcerative colitis (UC), representing chronic remittent or progressive conditions determined by non-specific inflammation and intestinal tissue damage

The receptor roles of its large extracellular domain rely on frontal and lateral interactions with other functional receptors to modulate various immune functions [3,4,5]