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For instance, a propensity to make an excessively intense innate immune response, or on the contrary the unability to control an infection, the pathogen persistence (potentially due to the previous cause), or a suboptimal functioning of mitochondria, leading to an excess production of reactive oxygen species (ROS), or a suboptimal functioning of the neurovegetative nervous system, facilitating the triggering of dysautonomia, or a propensity do develop autoimmune diseases

Yang et al., Development of mannosylated lipid nanoparticles for mRNA cancer vaccine with high antigen presentation efficiency and immunomodulatory capability

Bone marrow mesenchymal stem cell (BMSC)-derived EVs modified with an integrin -targeting peptide were found to enhance the efficacy of therapeutic regimens targeting pancreatic cancer by promoting the reprogramming of cancer-associated fibroblasts (CAFs) while inhibiting the pro-carcinogenic effects [62]

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Amyloid-beta aggregation: selective inhibition of aggregation in mixtures of amyloid with different chain lengths