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Notably, a neutralizing antibody MHM6 inhibited the secretion of TNF- induced by AIMP1 via competing with IgE for binding to CD23, suggesting that the interaction between AIMP1 and CD23 in monocytes might play an important role in autoimmune diseases

Association of plasma homocysteine with cardiometabolic multimorbidity: A cross-sectional study in northwest China

As an active component of celastrus and triperygium, celastrol exhibits significant broad-spectrum anticancer activities for the treatment of various cancers

A loss-of-function shRNA targeted screen in metastatic-derived cells identified Gstt1 , a member of the glutathione S -transferase superfamily, as uniquely required for dissemination and metastasis, but dispensable for primary tumour growth

Supporting gut lining integrity is another crucial function of probiotics

Laser treatments and microneedling typically show improvement after 3 to 6 sessions, while dermal fillers can provide immediate results