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Mice were then divided into cohorts that received either vehicle control (methocellulose grade A4M 0.5% w/v in milliQ water), or palbociclib (Cat# P-7788, LC Laboratories, Woburn, MA) dissolved in vehicle at 25 mg/mL

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Interestingly, PathVisio analysis comparing androgen-dependent with androgen-independent prostate cancer did not detect the Androgen Receptor Signaling Pathway as significantly dysregulated (Table 5)