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During lipid peroxidation, cyclic guanosine monophosphate (cGMP) is elevated, along with the downregulation of cyclic adenosine monophosphate (cAMP) concentration, leading to accelerated proliferation of epidermal cells in psoriasis ( Extensive experiments are proving that various subsets of T cells, including Th1, Th2, Th17, and regulatory T cells (Treg cell), as well as related cytokines, such as TNF-, IFN-, IL-23, and IL-17, engage in the pathogenesis of psoriasis (Deng et al., 2016)

Results GAS7 splicing isoforms To assess the possible involvement of GAS7 in phagocytosis, we examined the isoforms of GAS7 expressed in macrophages by comparing the molecular weights of various expressed, non-tagged GAS7 isoforms in HeLa cells to that of the endogenous GAS7 in RAW264.7 macrophages

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