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Sigma-Aldrich), and pelleted as above before undergoing flash freezing in liquid nitrogen and storage at 80C

This establishes a self-perpetuating cycle in which inflammation further enhances ROS production, exacerbating oxidative stress and tissue damage [4, 5]

94 Shekh-AhmadT.KovacS.AbramovA.WalkerM

& Canning-Clode, J

Pycnogenol attenuates the release of proinflammatory cytokines and expression of perilipin 2 in lipopolysaccharide-stimulated microglia in part via inhibition of NF-B and AP-1 activation