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The RseA and RshA anti-sigma factors and the Zur and NrdR repressors were identified as NaOCl-sensitive proteins and their oxidation resulted in an up-regulation of the SigH, SigE, Zur and NrdR regulons in the RNA-seq transcriptome

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1 Given the limited published data for onabotulinumtoxinA in the management of TN, it is not offered as a first-line treatment

Chronic kidney disease (CKD) reduces gut microbial diversity and induces compositional shifts (Peters et al