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Indeed, rapid and almost complete ATP restoration was found for ATP-depleted astrocytes 60 min after the application of glucose as energy substrate and of adenosine as substrate for AMP synthesis [60]

The activation of CHAC1 leads to GSH depletion, thereby increasing oxidative stress and lipid peroxide accumulation, hallmarks of ferroptosis

Int J Nanomed 13:83798393

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Brain energy metabolism and mitochondrial dysfunction in acute and chronic hepatic encephalopathy

In addition, a single dose of glutamine increases absolute T cell count (CD3+) and the count of CD8+ T cells but produces no effect on NK/neutrophils, CD4+/CD8+ ratio, or CD19+ lymphocytes [73]