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Additionally, BAZ also abrogates BSO-induced upregulation of total iNOS protein and its dimerization, while the PDI protein levels are unaffected

TIMP-1 and TIMP-2 tissue inhibitors of metalloproteinases are upregulated, further tipping the balance toward matrix preservation

Among these, the SNCA and MAPT loci demonstrate the strongest associations in European populations, while the GBA1 locus emerges as the principal risk gene in African populations (Rizig et al., 2023)

Australias Therapeutic Goods Administration (TGA) similarly reconfirmed that the drug is safe for use in pregnancy

Calcium signaling in airway smooth muscle cells: from physiology to pathophysiology