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FDA noted that an in-vitro pineal-gland study did not demonstrate a straightforward direct stimulation of melatonin release

The dose is deliberately high compared to classical peptides (5-10 mg for GLP-1 analogues, 2-5 mg for short regeneratives) because documented GHK-Cu protocols use larger quantities in trichological and cutaneous research (1-3 mg per injection, concentrated topical applications)

The liver is also an organ where ketone bodies are produced, and the concentration of one of them (-HB), increased several times as a consequence of the fasting intervention

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