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This approach may foster the creation of innovative therapies that specifically target neuronal insulin resistance (e.g., GLUT4 dysfunction) and enhance MCT2-mediated ketone uptake, thereby addressing the metabolic vulnerabilities of neurons and offering a promising pathway for intervening in neurodegenerative diseases (Antal et al., 2025)

Target proteins quantified through parallel reaction monitoring (PRM) For further confirming the proteomics data, fifty DEPs were selected and measured through PRM-MS analysis at Jingjie PTM BioLab (Hangzhou), Co, Ltd, Hangzhou, China

We further isolated primary PTCs from the Idh1 WT/Mut Ksp Cre mice underwent extensive cell death following cisplatin treatment, exhibiting morphological characteristics consistent with ferroptosis

Studies have shown that consuming full-fat yogurt can improve vitamin B12 status in individuals who are deficient in this vitamin

Glutamine, lymphocyte proliferation and cytokine production

And the research supporting this delivery method, while promising, comes with important caveats that every informed researcher should understand before making the switch