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GLP-1 Agonist Research: Mechanisms, Evidence, and Future Directions By Isaac Introduction GLP-1 agonists, also known as glucagon-like peptide-1 receptor agonists, represent a class of peptides that mimic the actions of the endogenous incretin hormone GLP-1

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IV = directly into the bloodstream

These peptides may not target lupus directly, but their mechanisms address symptoms or complications common in the disease

Zhang J, Xin S, Mao J, Liu X, Wang T, Liu J

Extended Data Figure 4 ENL depletion decreases the occupancies of total Pol II and Pol II S2P on ENL-bound genes