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Otherwise, bile duct-ligated rats commonly presented intracranial (superior sagittal sinus), portal and caval hypertension and aortal hypotension, gross brain swelling, hemorrhage and lesions, heart dysfunction, lung lesions, liver and kidney failure, gastrointestinal lesions, and severe arterial and venous thrombosis, peripherally and centrally

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The primary outcome is pre-MT recanalization, defined as reperfusion in over 50% of the affected area or no retrievable thrombus on initial digital subtraction angiography

8 , e1002493 (2012)

All authors reviewed, read and approved the manuscript