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223 In a randomized controlled trial in 30 women with fibromyalgia and vitamin D levels below 32 ng/mL, 1,200 IU (30 mcg) or 2,400 IU (60 mcg) of vitamin D3 daily, depending on baseline levels, for 20 weeks led to marked reduction in symptom severity and improved physical function compared with placebo

It had long been known that the disease was associated with defects in the gastrointestinal tract: patients had chronic gastritis and lack of acid secretion (achlorhydria)