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Crit Rev Oncog

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Among the key regulatory protein which may be targeted by the dehydro-alanine glutathione analog are Keap1 Nrf2, the sensing cysteine thiolate of which can be chemically modified by electrophiles (such as the lipid-derived HNE) and triggers the transcription of genes for antioxidant proteins and for the intermediate metabolism [143]

Effects of treatment with the antioxidant alpha-lipoic acid on cardiac autonomic neuropathy in NIDDM patients

Apart from directly modulating mitochondrial physiology, -synuclein oligomers also amplify cytosolic peroxide flux resulting in oxidation of glutathiones (Van Laar et al., 2020)

Application of metallomic and metabolomic approaches in exposure experiments on laboratory mice for environmental metal toxicity assessment