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We hypothesized that, in addition to metabolic alterations, other changes were occurring in the liver of Gclc KO mice, which could explain the lack of damage in the tissue

Moreover, -catenin recruits the transcription factor TCF4 to enhance SHMT2 expression, forming a positive feedback loop that sustains oncogenic signaling and promotes colorectal cancer cell proliferation and metastasis [139]

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Hong, M., Chen, D