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This study received ethical approval from the Institute of Animal Husbandry and Veterinary Medicines Animal Care and Use Committee (Permit number: IHVM11-23025)

The high Ca 2+ level in cytoplasm with mitochondria dysfunction and the low intracellular NAD + level both leads to the Warburg effect

Clinical studies in patients with severe lipodystrophy have shown that long-term leptin replacement therapy reverses hepatic and muscular IR and alleviates fasting hyperglycemia

Tekulu K, Taye G, Assefa D (2020) Effect of starter nitrogen and phosphorus fertilizer rates on yield and yield components, grain protein content of groundnut ( Arachis hypogaea L.), and residual soil nitrogen content in a semiarid north Ethiopia

Most evidence comes from animal studies or small preclinical trials

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues