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Psychiatry 16:1569826

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It is used in the treatment and prevention of vitamin B12 deficiency in patients with conditions such as:_ Addisonian (pernicious) anemia Malabsorption Atrophic gastritis Prolonged treatment with metformin Small bowel bacterial overgrowth (SIBO) Total or partial gastrectomy Infection with the fish parasite Diphyllobothrium latum Helicobacter pylori infection Pancreatic dysfunction Pancreatic or bowel malignancy Dietary deficiency (e.g

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The European Medicines Agency's Pharmacovigilance Risk Assessment Committee (PRAC) has identified ileus as an adverse reaction associated with GLP-1 receptor agonists, making this a recognised rather than merely theoretical risk

Shadowing: Shadowing under the eyes can occur due to structural variations such as tear trough deformity, which can create the illusion of darker circles