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NAD + /NADH is involved in this process within the mitochondria, where NAD + is reduced to NADH in the tricarboxylic acid (TCA) cycle and is subsequently oxidized to NAD + in the ETC for ATP generation

The GRU outputs (over time) fed to a 512-unit linear layer to obtain B.2 Decoder The decoders input is the latent tuple As shown in Figure 9, we use a shared-bottom architecture, which computes a shared embedding from the latent tuple, and then have one head for each of the In particular, we apply separate MLPs to each of the B.3 Training Because all DDSP components are differentiable, the model is differentiable end-to-end

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[224] demonstrated that oxidative stress triggers mtDNA leakage, which activates the cGASSTING pathway and induces the secretion of pro-inflammatory cytokines in human iPSC-derived neurons

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