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Loss of SLC33A1 leads to GSSG accumulation in the ER and a liposome-based assay demonstrates that SLC33A1 directly transports GSSG

doi: 10.2217/fmb.13.101 56 VallabhaneniS.ModyR

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Regorafenib (BAY 73-4506): a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity

In the current study, we examined early changes in the levels of oxidative stress and the expression of major presynaptic [synapsin-I, synaptophysin, growth-associated protein-43 (GAP-43), synaptosomal-associated protein-25 (SNAP-25)] and postsynaptic [drebrin, synapse-associated protein-97 (SAP-97), and postsynaptic density protein-95 (PSD-95)] proteins in hippocampal synaptosomes from IP-STZ and ICV-STZ treated rats (two different models of imparted insulin signaling)