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When it is released by the endothelial cells that line the blood vessels, NO prompts the surrounding smooth muscles to relax, causing vasodilation and thereby lowering blood pressure.[13] Lower NO levels are associated with the development of high blood pressure, heart disease, and ED.[14] Unfortunately, NO production declines with age

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This tissue is incapable of synthesizing L-carnitine, so they depend upon dietary and supplemental sources as well as the bodys own ability to manufacture it