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doi: 10.4252/wjsc.v7.i7.999 282 AmidfarMGarcezMLKimYK

Wnt and PI3K/Akt/mTOR survival pathways as therapeutic targets in glioblastoma

For ICP-MS, sample was treated with nitric acid 65% and measured in an Agilent 7500 ICP-MS (Agilent technologies, UK)

Active ingredients: Thioctic acid (in the form of Thioctic acid tromethamine) content of 300 mg

Normal rabbit IgG (polyclonal antibody, 2729, Cell Signaling Technologies) served as control

Paclitaxel, doxorubicin, and vincristine, known as MRP7 or MRP1 substrate drugs, were used as positive controls for different cell lines, and cisplatin as non-substrate for both MRP7 and MRP1 was used as the negative control