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Because it is unlikely that Glu would be modified by 4-OXO-DHA, our results support that 4-OXO-DHA (an electrophilic Michael acceptor) can covalently bind to the peptide containing the sequence of the active site of NF-B p50 protein to form a covalent linkage with the nucleophilic Cysteine-S 62 residue (marked in bold and italic in Table 1)

A 10mg/mL concentration works with every vial size and makes the math almost unnecessary

That is one of the biggest take home messages because we don't want everyone who gets this reaction to be using antibiotics unnecessarily, Blumenthal added

It is also why lyophilized powder (no water present) lasts so much longer than reconstituted solutions

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Why do I experience diarrhea while tapering off my steroid dose