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doi: 10.1056/NEJMoa1607887 44 CowanD

ALS disease-related mutations were reported to significantly accelerate the LLPS of both full-length FUS and FUS-LCD to form cross--aggregates, a highly stable fibril 39,64,67,68

In an attempt to further investigate the effect of LCA on flagellar expression, we performed scanning electron microscopy (SEM) to directly assess the presence and morphology of flagella in cultures treated with 100 M LCA or 1% DMSO for 24 h, focusing on the planktonic fractions due to sample preparation considerations and to provide a fairer basis for comparison