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High-dose B vitamin supplementation and cognitive decline in Alzheimer disease: a randomized controlled trial

Approval for the study protocols was granted by the Ethics Committee of Fujian Maternity and Child Health Hospital (Reference: 2021 KLRD09007) following a review that ensured compliance with relevant regulations, including the Measures for Ethical Review of Biomedical Research Involving Humans by the National Health Commission and the Declaration of Helsinki

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The potential of ethylene oxide to cause teratogenic or adverse reproductive effects has been examined in 4 animal species (mouse, rat, rabbit, and monkey) by 2 routes of administration