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131,132 PPAR can interact with the retinoid X receptor (RXR) to promote the transcription of target genes such as fatty acid transport protein 1 (FATP1), carnitine palmitoyltransferase I (CPTI), and medium-chain acyl-CoA dehydrogenase (MCAD) that contribute to fatty acid utilization including fatty acid uptake, thioesterification to fatty acyl-CoA, transport to mitochondria, and mitochondrial -oxidation