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Yoo, MD (EM Assistant Professor, San Antonio, TX), Alex Koyfman, MD (@EMHighAK), and Brit Long, MD (@long_brit) Case: A 55-year-old male with history of hypertension on hydrochlorothiazide presents to the emergency department (ED) with a chief complaint of a red, swollen, and painful left big toe

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The histidine at position 2 of GHK is therefore not interchangeable

It demonstrates significant anti-inflammatory properties through reduction of pro-inflammatory cytokines including TNF-alpha, IL-1 beta, and IL-6

Blood levels often improve within a few months

View Study Jzwiak M, Bauer M, Kamysz W, Kleczkowska P