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While early polymeric formulations such as NanoCurc established the foundational feasibility of systemic curcumin delivery in preclinical models [190, 191], specifically extending median survival from 28 to 63 days in xenograft models, recent researches have pivoted toward smart multifunctional nanocarriers designed to actively breach these stromal barriers and reprogram the TME [192]

Carbon Laser Peel: Called the Hollywood Peel by many, this procedure works on too much oil, dark spots, large pores, and patchy complexion

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They are characterized by a longer clinical history and have a better prognosis than primary GBM