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Promoter methylation of argininosuccinate synthetase-1 sensitises lymphomas to arginine deiminase treatment, autophagy and caspase-dependent apoptosis

Other small studies on enzyme inducers such as phenobarbital, phenytoin, rifampicin, omeprazole and carbamazepine have suggested that their effect on 2E1 is not significant, and thus they are unlikely to be responsible for excessive NAPQI formation when taken concurrently with paracetamol 45, 132, 133

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doi: 10.3390/cancers16213644 149 ProstyCKatergiKPapenburgJLawandiALeeTCShiHet al

Immune modulation Explored as a tuftsin analog for immunomodulatory activity, largely in animal and cell-based preclinical studies