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In some cases, blood clots have occurred (again, this is typically with a very high dosage, and it is possibly a complication of other medical conditions, or other medications which interact adversely with the B12)

Storing vials in clear glass under ambient light reduces potency by up to 40% within 48 hours

While B12 injections are commonly used to address deficiencies, some individuals may benefit from supplementation even if they are not deficient

Approach Loading Per-session dose 500-1,000 mg Schedule 3-5 consecutive days, then weekly/monthly Notes Clinic-supervised only

The effects of a B12 injection typically last 1-2 weeks initially, though this varies by individual

Maintaining consistent dosing intervals helps avoid accidental overdose