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Regulatory factors like heme oxygenase 1 (HO-1) and Poly(rC) binding proteins (PCBPs) also influence iron homeostasis, with HO-1 overexpression reducing ROS and lipid peroxidation to inhibit ferroptosis, as shown by Villalpando-Rodriguez et al

Metabolites were resolved across a 2.1 150 mm, 1.7 m Kinetex C18 column (Phenomenex) using a 5-min, reverse-phase gradient from a previously described method 19

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Total saponins from panax japonicus attenuate acute alcoholic liver oxidative stress and hepatosteatosis by P62-related nrf2 pathway and ampk-acc/ppar Axis in vivo and in vitro

Among them, the Ser-65 residue was generally conserved across all GST classes