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Munc13-4STX7 small-molecule docking strategy AlphaFold2-Multimer was used to generate the Munc13-4STX7 complex by submitting full-length human protein sequences of Munc13-4 (UniProt Q70J99) and STX7 (UniProt O15400) with default settings to create five relaxed models

variable.name Features & Storage Purity: 99% product.specification: 5-50mg/vial, 10vials/box Storage: Store at 2-8C or -20C according to protocol, protect from light

le trans-2-[[(2-[1,1'-biphnyl]-4-ylcyclopropyl) carbonyl]amino]-N-(2-chloro-6-mthylphnyl)-6-benzothiazolecarboxamide

For the broader research-only context on the compounds above, the linked cluster guides cover each compound in depth

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20 On the other hand, nucleophilic addition of the thiolate anion (MeS - ) is feasible and likely spontaneous (G = 4.4 and 7.7 kcal/mol for 4 and 5 , respectively