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However, neurological damage present for longer periods may be partially or completely irreversible, emphasising the importance of early diagnosis and treatment

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Relevance of glutathione S-transferase M1 and cytochrome P450 1A1 genetic polymorphisms to the development of head and neck cancers

Antioxid Redox Signal 22(16):13821424 Tsuchiya Y, Endo Y, Sato H, Okada Y, Mai M, Sasaki T, Seiki M (1994) Expression of type-IV collagenases in human tumor cell lines that can form liver colonies in chick embryos

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Insulin resistance alone does not result in the development of type 2 diabetes, and reports have shown that there must be progressive dysfunction of pancreatic islets, which disrupt the secretion of glucagon from the cells and insulin from cells, leading to uncontrolled hyperglycaemia, for the disease to develop [220]