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However, an in vivo exposure chamber study of diesel exhaust found that vitamin C and N-acetylcysteine (NAC) supplementation increased vasoconstriction caused by exposure, and another study of acute exposure to ambient PM and/or ozone found no effects on cardiovascular outcomes

Sakuma, T., Nakade, S., Sakane, Y., Suzuki, K

Therefore, unraveling the connection between these pathways and the notable pathological mechanisms observed during PD progression could enhance our comprehension of the diseases origin and provide valuable insights into potential molecular targets for the developing therapeutic interventions

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