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Higher doses of aspartame are also associated with seizures in humans and animals

10.7499/j.issn.1008-8830.2019.07.009 Zhongguo Dang Dai Er Ke Za Zhi 152 ZhaoT.SchiweckC.JamalambadiH.MeyerK.BrandtE.SchneiderM.et al (2025)

(3) Increased neutrophil extracellular traps (NETs) Neutrophils may kill the invading pathogens including viruses not only through engulfment of microbes, the formation of reactive oxygen species, degranulation, and secretion of antimicrobials but also through formation of NETs

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78 ManickiM.MajewskaJ.CiesielskiS.SchilkeB.BlenskaA.KominekJ.et al (2014)

"Untreated fever, particularly in the first trimester, increases the risk of miscarriage, birth defects, and premature birth, and untreated pain can lead to maternal depression, anxiety, and high blood pressure," the society said in its statement